Lipovax-Fg115
Lipovax-Fg115 is an adjuvanted delivery vehicle for recombinant antigens.
The platform exploits the commonly used his-tag to attach multiple copies of one or more type of antigens to the surface Lipovax-Fg115 particles.
Our proprietary Fg115 molecules are also attached to the liposomes to stimulate the TLR5 receptor. The platform improves vaccine internalisation by dendritic cells and results in increased cross presentation. In vivo this translates in increased T cell and antibody and responses.
Benefits of Lipovax-Fg115
Optimal size for dendritic cell uptake and processing
Improved internalisation and cross presentation
Synthetic and well defined components
Not based on cationic liposomes
Good safety profile
Simple formulation
High homogeneity and reproducibility
Antigen stabilisation and half life improvement
Applicable to antigens of varying size (from peptides to large proteins)
